The genetic editing of human embryos through a molecular biology manipulation known as CRISPR surely sent shock waves across the globe. Many felt that He Jiankui, the Chinese scientist who carried out the experiments had opened Pandora’s box. Yet, as people had now some time to ponder over the events, the scientific establishment has […]
Ariel Fernandez Drug designers often implement molecular therapies to block malfunctioning proteins that are causing disease. They do so by creating small molecules that bind to the intended protein target when suitably delivered. The procedure has its risks as unintended targets (off-target proteins) may also be hit or impaired, especially when they are structurally similar (homologous) […]
“Physics at the Biomolecular Interface” is the latest book by Ariel Fernandez (阿列尔·费尔南德斯), the physical chemist and mathematician who developed the center manifold thermodynamics, unraveling the physical basis for the onset of life, and discovered the dehydron (脱水元), an idea that laid the foundation for the new field of epistructural biology. The hardcover is expected by June 8, 2016. The bibliographic information […]
On 26 June 2015, Science magazine published an article in its section “Policy Forum” entitled “Promoting an Open Research Culture” (B. A. Nosek et al. Science, Vol. 348, pp. 1422-1425, DOI: 10.1126/science.aab2374). The article and two related pieces (“Self-correction in science at work”, and “Solving reproducibility“) published in the same issue seem to have been inspired by the perception that there […]
Ariel Fernandez (阿列尔·费尔南德斯, also styled as Ariel Fernandez Stigliano, CV linked and updated 5/18/2015) is a physical chemist and mathematician and the former Karl F. Hasselmann Endowed Chair Professor of Bioengineering at Rice University. He got his Ph. D. in record time from Yale University under the guidance of Oktay Sinanoglu (who recently passed away according to Yale News). Completed […]
“Residents and interns worked a lot of hours, and I wrote honestly about what it was like to be an intern. One of the deans wasn’t crazy about that. It reminded me that my core identity is as a journalist, constantly challenging things…Blogs are powerful and lower the publishing barrier.” Ivan Oransky This post constitutes […]